Roche for a Better Future Challenge: Advancing Digital Innovation for Women Living with Breast Cancer

Breast cancer remains one of the most complex, personal, and emotionally demanding medical journeys in women’s health today. Even with major advances in diagnostics, targeted therapies, and survivorship care, the day-to-day reality of women living with breast cancer is still marked by uncertainty, fatigue, emotional strain, and the need to manage long and intricate treatment pathways. Many women must balance demanding regimens with the rest of their lives, often without continuous support between clinic visits. For health systems, this creates a persistent gap: clinical excellence is strong, but real-life continuity and personalized guidance are often missing.

To help address these challenges, the Roche for a Better Future Breast Cancer Innovation Challenge was launched. The initiative was designed to identify and accelerate digital innovations that elevate the breast cancer care journey. Launched in partnership with Roche Israel, Sheba Medical Center, and supported by Startup Nation Central, in collaboration with ARC, the challenge focused on strengthening treatment adherence, enabling personalized disease management, and improving quality of life for women with breast cancer.

The Roche for a Better Future challenge brings together Israels most promising digital health companies, reflecting the country’s leadership in AI, behavioral health, clinical software, and patient centered design. In 2025, more than thirty startups applied, showcasing a wide spectrum of digital approaches to help women navigate breast cancer with greater clarity, confidence, and support. A rigorous evaluation process followed, guided by an advisory committee representing ARC Oncology, Almeda Ventures, 8400 Health Network, and leading clinicians from Rambam, Sheba, and Hadassah oncology departments. Together they selected five finalists, each offering a distinct solution that shows how digital innovation can close critical gaps in the breast cancer care journey.

Datos Health

Datos is an AI-driven hybrid care automation platform that helps healthcare organizations expand capacity beyond the clinic walls. Replacing rigid RPM systems, Datos automates personalized remote and hybrid care pathways, integrates real-time monitoring, and captures patient-reported outcomes to unlock smarter, proactive care. By orchestrating dynamic education, virtual visits, and tailored interventions, Datos boosts patient adherence while easing clinician workload and improving efficiency. The platform enables health systems to deliver more continuous, connected, scalable care without adding staff or infrastructure, driving measurably safer, higher-quality outcomes so teams can focus on what matters most: stronger patient relationships and long-term sustainable care delivery.

WizeCare

WizeCare is an advanced, clinically proven physiological rehabilitation platform used by clinicians and hundreds of thousands of patients worldwide. Backed by three clinical studies with leading global institutions and protected by a motion-analysis technology patent, WizeCare delivers AI-powered assessment, personalized treatment, and continuous monitoring. The platform supports a wide range of chronic and acute conditions, including orthopedics, women’s health, oncology, pediatrics, geriatrics, and neurological rehab. For breast cancer patients, WizeCare provides targeted rehabilitation protocols that improve quality of life, enhance medication adherence, reduce stress and depressive symptoms, and help lower reliance on opioid pain medication.

Effectivate

Effectivate offers a cognitive-training platform built on accessible, evidence-based exercises developed by leading experts. Our mission is to strengthen cognitive resilience across the lifespan, helping individuals maintain cognitive skills and regain confidence. Through adaptive gamified tasks, clear progress feedback, and psychoeducational content, users are motivated to train consistently and build habits that support cognitive health and emotional well-being. The platform is widely adopted, with over 35K users and more than 40M completed training games, and is used across clinical, community, and organizational settings seeking an effective, personalized cognitive-health solution.

Dosentrx

Dosentrx’s ReX platform improves specialty oral medication management by combining precise dosing, real-time adherence visibility, and continuous care coordination. ReX administers each dose directly to the patient while gathering real-time clinical information through guided check-in questions. Care teams review patient behavior and responses in the secure, cloud-based ReX Treatment Manager and adjust treatment plans as needed, with updates syncing automatically via cellular connection. This closed-loop system reduces uncertainty by providing reliable, actionable data and supporting flexible, patient-specific care. ReX enables care teams to improve outcomes, enhance treatment effectiveness, and deliver responsive, high-quality home care for complex oral specialty medications.

YuviTal Winner of the 2025 Challenge

After a highly competitive evaluation, YuviTal was selected as the winner. YuviTal brings together live data, personalized behavioral guidance, and emotional support in a single continuous layer tailored to women with breast cancer.

YuviTal is a digital health platform dedicated to transforming behavior and improving health outcomes through personalized engagement, gamification, and data-driven insights. For women facing breast cancer, YuviTal provides continuous emotional, physical, and social support, empowering them to take an active role in their care journey. The platform integrates personalized health goals, mental well-being tools, and community engagement features to promote resilience and treatment adherence. By combining clinical science with motivational psychology, YuviTal enhances quality of life, strengthens patient–care team communication, and bridges the gap between healthcare systems and real-life patient experience.

While all finalists showed strong potential, YuviTal stood out for its holistic approach and ability to integrate data driven personalization, behavioral psychology, emotional support, and clinical relevance. The platform strengthens both the patient experience and the provider workflow, making it highly suitable for real-world deployment.

As the winner, YuviTal will receive up to 250,000 NIS to run a clinical pilot at Sheba Medical Center, fast track Helsinki Committee approval, and global mentorship through Roche’s international network. This pilot will evaluate how YuviTal’s behavior-based platform can boost adherence and create more connected care experiences for women with breast cancer.

Looking Ahead

The Roche for a Better Future Challenge demonstrates what is possible when industry leaders, clinical experts, and innovative startups collaborate to elevate women’s health. Breast cancer remains one of the most significant health challenges globally, and yet many aspects of the patient journey remain underserved. Digital tools that enhance communication, emotional wellbeing, lifestyle management, and daily continuity play an increasingly important role in shaping the future of oncology.

This year’s finalists reflect the strength and depth of Israels health tech ecosystem. Each company addressed a different piece of the breast cancer puzzle, and together they demonstrated how technology can make care more personalized, more consistent, and more humane. YuviTal’s victory represents an important step toward continuous, data informed, and compassionate care that meets women where they are.